The 30-share index was trading lower by 40.86 points, or 0.14 per cent, at 27,603.02, with stocks of oil & gas, power, realty, PSUs, auto and IT sectors pulling it down.
On similar lines, the NSE Nifty shed 15.80 points, or 0.34 per cent, at 8,341.50.
The Sensex had tumbled 313.62 points in the previous session on widespread profit-booking amid lower-than-expected earnings from ITC.
Brokers said sustained selling by participants and caution ahead of monthly expiry in the derivatives segment on Thursday amid a mixed trend at other Asian markets led to the fall.
Shares of Tata Motors were trading 1.52 per cent down at Rs 497.50 ahead of its quarterly earnings.
Among other Asian markets, Hong Kong’s Hang Seng was up 1.68 per cent while Japan’s Nikkei slid 0.10 per cent in early trade today.
The US markets were closed yesterday for a public holiday.
PTI