The report says the quake struck Saifabad village near the town of Khonj, about 1,000 kilometers south of the capital, Tehran.
The TV says the four fatalities are foreign nationals, a reference to Afghan laborers who work on farms. It says another four people were injured.
The epicenter of the quake is said to be in a mountainous and sparsely populated rural area.
The US Geological Survey described the temblor as a 5.3 magnitude quake, striking at a shallow depth of 10 kilometers in Iran’s Fars province.
Magnitude 5 earthquakes can cause considerable damage.
Friday’s quake also struck at a shallow depth, which intensifies its effect.
PTI